Science 360 (NSF, March 7) -- A new study offers the first atomic-scale view of an interaction between the HIV capsid – the protein coat that shepherds HIV into the nucleus of human cells – and a host protein known as cyclophilin A. This interaction is key to HIV infection, researchers say. Physics professor Klaus Schulten, postdoctoral researcher Juan Perilla, and their colleagues used experimental data and computer simulations to determine how a human protein that aids HIV infection binds to the HIV capsid.